Synthesis, structure and biological activity of α-trifluoromethyl-substituted thyreotropin releasing hormone

DOI: 10.1016/S0022-1139(96)03461-6

Source and publish data:

Journal of Fluorine Chemistry p. 53 - 57 (1996)

Update date:2022-07-29

Topics:

Authors:

Koksch, Beate

Ullmann, Dirk

Jakubke, Hans-Dieter

Burger, Klaus

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0022-1139(96)03461-6

The incorporation of α-trifluoromethyl pyroglutamic acid into thyreotropin releasing hormone TRH, results in the complete stability of the pGlu-His bond against proteolytic degradation by pyroglutamyl aminopeptidase II. The influence of the trifluoromethy

Full text of DOI:10.1016/S0022-1139(96)03461-6

Products guided by the article

Product name:Glutamic acid, N-[(phenylmethoxy)carbonyl]-2-(trifluoromethyl)-, 1-methyl ester

Cas No:129398-31-8

R&D Labs maybe for 129398-31-8

zhengzhou Triz Pharma-Tech Co., Ltd

website:http://www.Trizpharma-tech.com

Contact:+86-0371-86597269，53392065

Address:High-tech Industrial Development Zone, Zhengzhou City, NO.7 Holly Street
Shandong Dayi Chemical Co., Ltd.

website:http://www.dayi.com.cn

Contact:+86- 535-7388728. 15306386031

Address:No 1 Danya west road, Laiyang City, Shandong province
jiangsu haian chemical co.,ltd.

Contact:86-513-15851283853

Address:No.99,Changjiang West Road,Haian County,Jiangsu Province,China
Puyang Willing Chemicals Co.,Ltd.

Contact:86-393-4840366

Address:Puyang Henan China
Xiamen Huasing Chemicals Co.Ltd.

Contact:0086-592-6228397

Address:NO.24, Xinglin North 2nd Road,Jimei district

Relevant to this article

Direct Synthesis of 2-Formylpyrrolidines, 2-Pyrrolidinones and 2-Dihydrofuranones via Aerobic Copper-Catalyzed Aminooxygenation and Dioxygenation of 4-Pentenylsulfonamides and 4-Pentenylalcohols

Doi:10.1021/jacs.7b05680
(2017)
Singly and Doubly Quinoxaline-Fused B^III Subporphyrins

Doi:10.1002/chem.201904151
(2019)
An expeditious and efficient synthesis of highly functionalized [1,6]-naphthyridines under catalyst-free conditions in aqueous medium

Doi:10.1021/ol201877v
(2011)
Graphene oxide (GO)-catalyzed multi-component reactions: Green synthesis of library of pharmacophore 3-sulfenylimidazo[1,2-a]pyridines

Doi:10.1039/c5ra04983k
(2015)
Rhodium(i) complexes bearing N-donor ligands: Catalytic activity towards intramolecular cyclization of alkynoic acids and ligand lability

Doi:10.1039/c1nj20094a
(2011)
Synthesis and anticonvulsant evaluation of some novel 4(3H)-quinazolinones

Doi:10.1007/s00706-011-0525-3
(2011)

Article Doi