
Tetrahedron Letters p. 1531 - 1534 (1990)
Update date:2022-07-30
Topics:
Walkup
Kane
Obeyesekere
β-Chloroethyldimethylsilyl enol ether derivatives of five ketones were allowed to react with tributylstannane in the presence of AIBN to yield the products of 'reductive α-alkylation', 1-oxa-2-silacyclohexanes, plus ethyldimethylsilyl enol ether byproducts from direct reduction. The unstable oxasilacyclohexanes were treated with methyllithium to yield, upon workup, γ-(trimethylsilyl) alcohols.
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