Use of the 2,4-dinitrobenzyl protecting group in the synthesis of phosphorodithioate analogues of oligodeoxyribonucleotides

Article abstract of DOI:10.1016/S0040-4039(00)88796-1

The putative intermediate bis(1,2,4-triazolide) derivative (5) is used in the stepwise synthesis in solution of the phosphorodithioate analogue (10) of thymidylyl-(3'→5')-thymidylyl-3(3'→5')-thymidine; the 2,4-dinitrobenzyl (Dnb) group is used to protect