The synthesis of 6-C-substituted 9-methoxymethylpurine derivatives

Article abstract of DOI:10.1002/jhet.5570270403

6-Cyanomethylene (2), which was prepared via 1 by substitution with malononitrile, has been catalytically hydrogenated to the α-(aminomethylene)-9-(methoxymethyl)-9H-purine-6-acetonitrile (3) in good yield using N,N-dimethylformamide-benzene as solvent ov