Tetrahedron Letters p. 1471 - 1474 (1990)
Update date:2022-08-02
Topics:
Freer, Andrew
Overton, Karl
Tomanek, Richard
Cycloaddition of nitrone (2) to α-chloroacrylonitrile followed by hydrolysis afforded the isoxazolidinone (1) as a single diastereomer.The configuration at the new chiral centre (3S), corresponding to that in thienamycin, was established by an X-ray analy
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