The Synthesis of 4-Alkylsulphonyl-5-amino- and 5-Amino-4-phosphono-imidazole Nucleosides as Potential Inhibitors of Purine Biosynthesis

DOI: 10.1039/P19900000955

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 955 - 963 (1990)

Update date:2022-08-05

Topics:

Authors:

Buchanan, J. Grant

McCaig, Avril E.

Wightman, Richard H.

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Article abstract of DOI:10.1039/P19900000955

Conversion of 4(5)-methylthio-5(4)-nitroimidazole (11) into its silyl derivative and subsequent condensation with 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose (9) in the presence of trimethylsilyl trifluoromethanesulphonate for a short reaction time ga

Full text of DOI:10.1039/P19900000955

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