Synthesis and Antiviral Activity of Some 3'-C-Difluoromethyl and 3'-Deoxy-3'-C-fluoromethyl Nucleosides

Article abstract of DOI:10.1021/jm00171a024

The synthesis and antiviral activity of a number of 3'-C-difluoromethyl and 3'-deoxy-3'-C-fluoromethyl nucleosides are reported.The 3'-C-difluoromethyl nucleosides 26a and 26b were obtained by treatment of the corresponding 2',5'-di-O-protected-3'-C-formy