ASYMMETRIC SYNTHESIS WITH CHIRAL β-LACTAMS. HIGHLY STEREOSELECTIVE ALKYLATION AND ALDOL REACTION OF A CHIRAL 3-AMINO-4-STYRYL-β-LACTAM

DOI: 10.1016/S0040-4039(00)94407-1

Source and publish data:

Tetrahedron Letters p. 977 - 980 (1990)

Update date:2022-08-05

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Authors:

Ojima, Iwao

Pei, Yazhong

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Article abstract of DOI:10.1016/S0040-4039(00)94407-1

Extremely stereoselective alkylation and aldol reaction of enantiomerically pure 3-amino-4-styryl-β-lactams and a application to the asymmetric synthesis of α,β-diamino acid and alcohol are described.Possible mechanisms for these reactions are proposed.

Full text of DOI:10.1016/S0040-4039(00)94407-1

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