ASYMMETRIC SYNTHESIS WITH CHIRAL β-LACTAMS. HIGHLY STEREOSELECTIVE ALKYLATION AND ALDOL REACTION OF A CHIRAL 3-AMINO-4-STYRYL-β-LACTAM

Article abstract of DOI:10.1016/S0040-4039(00)94407-1

Extremely stereoselective alkylation and aldol reaction of enantiomerically pure 3-amino-4-styryl-β-lactams and a application to the asymmetric synthesis of α,β-diamino acid and alcohol are described.Possible mechanisms for these reactions are proposed.