Deoxy sugar analogues of triciribine: Correlation of antiviral and antiproliferative activity with intracellular phosphorylation

DOI: 10.1021/jm990205m

Source and publish data:

Journal of Medicinal Chemistry p. 2438 - 2448 (2000)

Update date:2022-08-04

Topics:

Authors:

Porcari, Anthony R.

Ptak, Roger G.

Borysko, Katherine Z.

Breitenbach, Julie M.

Vittori, Sauro

Wotring, Linda L.

Drach, John C.

Townsend, Leroy B.

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Article abstract of DOI:10.1021/jm990205m

Triciribine (TCN) and triciribine monophosphate (TCN-P) have antiviral and antineoplastic activity at low micromolar or submicromolar concentrations. In an effort to improve and better understand this activity, we have conducted a structure - activity rel

Full text of DOI:10.1021/jm990205m

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