Solution phase synthesis of dithymidine phosphorodithioate using new S- protecting groups in combination with a chemoselective coupling reagent (PyNOP)

Article abstract of DOI:10.1080/07328319708002518

A method for the synthesis of O-thymidin-3'-yl S-alkyl dithiophosphate monomers 1 with different S-protecting groups has been developed. These have been used for solution phase synthesis of dithymidine phosphorodithioate by a new phosphotriester method. C

Full text of DOI:10.1080/07328319708002518

Nucleosides and Nucleotides
ISSN: 0732-8311 (Print) (Online) Journal homepage: http://www.tandfonline.com/loi/lncn19
Solution Phase Synthesis of Dithymidine
Phosphorodithioate Using New S-Protecting
Groups in Combination with a Chemoselective
Coupling Reagent (PyNOP)
Jan Kehler , Ask Püschl & Otto Dahl
To cite this article: Jan Kehler , Ask Püschl & Otto Dahl (1997) Solution Phase Synthesis of
Dithymidine Phosphorodithioate Using New S-Protecting Groups in Combination with a
Chemoselective Coupling Reagent (PyNOP), Nucleosides and Nucleotides, 16:1-2, 23-32, DOI:
10.1080/07328319708002518
To link to this article: http://dx.doi.org/10.1080/07328319708002518
Published online: 20 Aug 2006.
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Date: 06 June 2016, At: 06:15