The Synthesis and Biophysical Investigations of Novel Ring-Expanded Nucleosides, Nucleotides, and Homopolymers Containing the 5:7-Fused Heterocyclic Ring System Imidazodiazepine

Article abstract of DOI:10.1021/jo00310a021

The synthesis and conformational studies of two isomeric 5:7-fused nucleosides, 4,5,7,8-tetrahydro-6H-3-(β-D-ribofuranosyl)imidazo<4,5-e><1,4>diazepine-5,8-dione (1) and its 1-glycosyl analogue (2), their respective 5'-mono- and -diphosphate derivatives (