Catalytic asymmetric hydroxylation of α-alkoxycarbonyl amides with a Pr(OiPr)3/amide-based ligand catalyst

DOI: 10.1016/j.tetlet.2010.11.064

Source and publish data:

Tetrahedron Letters p. 2140 - 2143 (2011)

Update date:2022-08-02

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Authors:

Takechi, Sho

Kumagai, Naoya

Shibasaki, Masakatsu

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Article abstract of DOI:10.1016/j.tetlet.2010.11.064

A catalytic asymmetric hydroxylation of N-nonsubstituted α-alkoxycarbonyl amides is described. A new effective catalyst comprising Pr(OⁱPr)₃ and a fluoro-substituted amide-based ligand was identified using oxaziridine as the oxidizin

Full text of DOI:10.1016/j.tetlet.2010.11.064

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