Synthesis and Circular Dichroism of Optically Pure (+/-)-(1S,2S,5S)-5-Methoxy-3,4,6,7-tetramethylidenebicyclooct-2-yl Derivatives. Baker's Yeast Reduction of 4-Methoxy-5,6,7,8-tetramethylidenebicyclooctan-2-one

Article abstract of DOI:10.1002/hlca.19900730425

Baker's yeast reduction of 4-methoxy-5,6,7,8-tetramethylidenebicyclo<2.2.2>octan-2-one (11) under fermenting conditions afforded (-)-(1S,2S,4R)-4-methoxy-5,6,7,8-tetramethylidenebicyclo<2.2.2>octan-2-ol ((-)-13) in 60percent yield with an e.e. > 99.5perce