A convergent process to C-2 substituted penems via addition of thiols and organocuprates to an O-triflylthioketene acetal

Article abstract of DOI:10.1016/S0040-4039(00)89046-2

The synthesis of fully protected penem derivatives has been achieved by addition of thiols and both higher and lower order cuprates to a novel 2-O-triflylpenem.