A NOVEL AND EFFICIENT ROUTE TO CHIRAL 2-SUBSTITUTED CARBOCYCLIC 5'-N-ETHYL-CARBOXAMIDO-ADENOSINE (C-NECA)

DOI: 10.1016/S0040-4039(01)93795-5

Source and publish data:

Tetrahedron Letters p. 5543 - 5546 (1989)

Update date:2022-09-26

Topics:

Authors:

Chen, Jen

Grim, Michael

Rock, Caren

Chan, Kenneth

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Article abstract of DOI:10.1016/S0040-4039(01)93795-5

A series of chiral 2-substituted-carbocyclic-NECA analogs was prepared in seven steps with an efficient resolution.The overall yield is good and can be applied to the other carbocyclic nucleosides.

Full text of DOI:10.1016/S0040-4039(01)93795-5

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