A Ring-Enlarged Oxetanocin A Analogue as an Inhibitor of HIV Infectivity

DOI: 10.1021/jm00105a054

Source and publish data:

Journal of Medicinal Chemistry p. 343 - 349 (1991)

Update date:2022-07-29

Topics:

Authors:

Tseng, Christopher K-H.

Marquez, Victor E.

Milne, George W. A.

Wysocki, Roland J.

Mitsuya, Hiroaki

et al. et al.

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Article abstract of DOI:10.1021/jm00105a054

Two ring-expanded analogues (compounds 2 and 3) of the anti-HIV fermentation product oxetanocin A (1) were synthesized from commercially available diacetone D-glucose.Antiviral testing against HIV in ATH8 cells revealed that the ring-expanded analogue 2 p

Full text of DOI:10.1021/jm00105a054

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