Synthesis and antirhinovirus activity of 8-substituted analogues of 6-(dimethylamino)-9-(4-methylbenzyl)-2-(trifluromethyl)-9H-purine

DOI: 10.1021/jm00105a023

Source and publish data:

Journal of Medicinal Chemistry p. 157 - 160 (1991)

Update date:2022-08-03

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Authors:

Kelley Kelley

Linn Linn

Selway Selway

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Article abstract of DOI:10.1021/jm00105a023

Several 8-substituted analogues of 6-(dimethylamino)-9-(4-methylbenzyl)-2-(trifluoromethyl)-9H-purine (1) were synthesized and tested for activity against rhinovirus type 1B. Among 16 8-substituted analogues, the 8-amino (3) and 8-bromo (2) analogues were

Full text of DOI:10.1021/jm00105a023

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Product name:[8-Bromo-9-(4-methyl-benzyl)-2-trifluoromethyl-9H-purin-6-yl]-dimethyl-amine

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