Synthesis and biological evaluation of novel 4-benzylpiperazine ligands for sigma-1 receptor imaging

DOI: 10.1016/j.bmc.2011.03.037

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Bioorganic and Medicinal Chemistry p. 2911 - 2917 (2011)

Update date:2022-07-29

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Authors:

Li, Zi-Jing

Ren, Hui-Ying

Cui, Meng-Chao

Deuther-Conrad, Winnie

Tang, Rui-Kun

Steinbach, J?rg

Brust, Peter

Liu, Bo-Li

Jia, Hong-Mei

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Article abstract of DOI:10.1016/j.bmc.2011.03.037

We report the synthesis and evaluation of 4-benzylpiperazine ligands (BP-CH₃, BP-F, BP-Br, BP-I, and BP-NO₂) as potential σ₁ receptor ligands. The X-ray crystal structure of BP-Br, which crystallized with monoclinic space

Full text of DOI:10.1016/j.bmc.2011.03.037

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