Sodium channel binding and anticonvulsant activities of hydantoins containing conformationally constrained 5-phenyl substituents

DOI: 10.1002/jps.2600791005

Source and publish data:

Journal of Pharmaceutical Sciences p. 871 - 874 (1990)

Update date:2022-08-03

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Authors:

Brouillette

Brown Brown

DeLorey DeLorey

Liang Liang

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Article abstract of DOI:10.1002/jps.2600791005

As a preliminary investigation of the importance of the aromatic ring orientation in interactions of 5-phenylhydantoins with the anticonvulsant site on the neuronal voltage-sensitive sodium channel, two isomeric hydantoins containing conformationally cons

Full text of DOI:10.1002/jps.2600791005

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