Glycomimetic building blocks: A divergent synthesis of epimers of shikimic acid

DOI: 10.1021/ol201252x

Source and publish data:

Organic Letters p. 3790 - 3793 (2011)

Update date:2022-09-26

Topics:

Authors:

Grim, Joseph C.

Garber, Kathleen C. A.

Kiessling, Laura L.

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Article abstract of DOI:10.1021/ol201252x

A divergent synthesis of (-)-4-epi-shikimic acid was developed. This route features a one-pot zinc-mediated reductive ring opening of an arabinofuranose followed by a Barbier reaction and culminates in a ring-closing metathesis. Functionalization of (-)-4

Full text of DOI:10.1021/ol201252x

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