A synthesis of α-substituted trans-α, β-dibenzyl-γ-butyrolactones: Diastereofacial differentiation in the electrophilic attack on the metal enolates of α, β-dibenzyl-γ-butyrolactones

Article abstract of DOI:10.1016/S0040-4039(00)94458-7

α-Substituted trans-α, β-dibenzyl-γ-butyrolactones were synthesized in a diastereoselective manner by the reaction of the potassium enolates of α, β-dibenzyl-γbutyrolactones with electrophiles. The method was applied to the synthesis of (±)trachelogenin.