Design, synthesis and in vitro drug release investigation of new potential 5-FU prodrugs

DOI: 10.1016/j.ejmech.2011.04.010

Source and publish data:

European Journal of Medicinal Chemistry p. 2867 - 2879 (2011)

Update date:2022-08-05

Topics:

Authors:

Daumar, Pierre

Decombat, Caroline

Chezal, Jean-Michel

Debiton, Eric

Madesclaire, Michel

Coudert, Pascal

Galmier, Marie-Josphe

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Article abstract of DOI:10.1016/j.ejmech.2011.04.010

In order to identify new efficient prodrugs of 5-fluorouracil (5-FU) and to develop an original targeting approach using 2-fluoro-2-deoxyglucose (FDG) as a potential drug carrier, eight original 5-FU derivatives were synthesized: 5-FU was attached by the

Full text of DOI:10.1016/j.ejmech.2011.04.010

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