Tetrahedron Letters p. 5745 - 5748 (1990)
Update date:2022-08-05
Topics:
Guy
Ahmad
Teoule
Deoxyribosylurea is an alkali sensitive DNA defect induced by the action of ionizing radiation. Oligonucleotides bearing this residue were synthesized using 5'-O-(4-methoxytrityl)-2'-deoxyribosylurea-3'-O-(2-cyanoethyl-N,N'-dii sopropyl)phosphoramidite and PAC protected deoxynucleoside phosphoramidites.
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