
Tetrahedron Letters p. 4985 - 4986 (1990)
Update date:2022-07-29
Topics:
Polt
Peterson
Sequential addition of iBu2AlH and RLi or RMgX to Schiff base esters derived from amino acids provides a simple route to β-amino alcohols. The reaction procedes without racemization, and with high threo selectivity. Several representative sphingosines are synthesized.
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Doi:10.1080/15421406.2011.566081
(2011)Doi:10.2174/157017809789124858
(2009)Doi:10.1021/jm00107a022
(1991)Doi:10.1021/jm300628c
(2012)Doi:10.1016/j.tet.2011.05.065
(2011)Doi:10.1039/DT9900003531
(1990)