The First Enantioselectice Total Syntheses of the Allopumiliotoxin A Alkaloids 267A and 339B

DOI: 10.1021/jo00030a026

Source and publish data:

Journal of Organic Chemistry p. 1179 - 1190 (1992)

Update date:2022-07-29

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Authors:

Goldstein, Steven W.

Overmann, Larry E.

Rabinowitz, Michael H.

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Article abstract of DOI:10.1021/jo00030a026

Short, highly stereocontrolled, asymmetric total syntheses of the title amphibian alkaloids are described.In the first stage the indolizidine ketone 11 is assembled from L-proline in enantiomerically pure form.This short sequence proceeds in five laborato

Full text of DOI:10.1021/jo00030a026

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