
Journal of Organic Chemistry p. 1179 - 1190 (1992)
Update date:2022-07-29
Topics:
Goldstein, Steven W.
Overmann, Larry E.
Rabinowitz, Michael H.
Short, highly stereocontrolled, asymmetric total syntheses of the title amphibian alkaloids are described.In the first stage the indolizidine ketone 11 is assembled from L-proline in enantiomerically pure form.This short sequence proceeds in five laborato
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