Diastereoselective photochemical synthesis of 3,3'-disubstituted indolines

Article abstract of DOI:10.1016/S0040-4020(97)10028-X

Spiroindoline lactams 9 and imides 11 were efficiently and diastereoselectively prepared by photocyclization of N-arylenaminolactams 8 and esters 5 respectively. Imides 11 wee conveniently transformed into the known indolines 13 and 14 which are key intermediates for the synthesis of (±)-vindorosine and Aspidosperma alkaloids.