Synthesis of the aspidosperma skeleton through allylsilane N-acyliminium cyclization

Article abstract of DOI:10.1016/S0040-4020(01)90540-X

A highly stereoselective synthesis of the Aspidosperma ring system is described, based on a combination of two stereocontrolled processes. The first features a base-catalyzed cyclization of the imine 5 to generate the indoline 4. The second involves the f