Catalytic sulfur ylide reactions: Use of diazoacetamides for the diastereoselective synthesis of glycidic amides

DOI: 10.1016/S0040-4039(98)01852-8

Source and publish data:

Tetrahedron Letters p. 8517 - 8520 (1998)

Update date:2022-09-26

Topics:

Authors:

Aggarwal, Varinder K.

Blackburn, Paul

Fieldhouse, Robin

Jones, Ray V. H.

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Article abstract of DOI:10.1016/S0040-4039(98)01852-8

Diazoacetamides react with aldehydes in the presence of catalytic quantities of Cu(acac)₂ (5 mol%) and tetrahydrothiophene (20 mol%) to give glycidic amides in good yields and high diastereoselectivity.

Full text of DOI:10.1016/S0040-4039(98)01852-8

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