Catalytic sulfur ylide reactions: Use of diazoacetamides for the diastereoselective synthesis of glycidic amides

Article abstract of DOI:10.1016/S0040-4039(98)01852-8

Diazoacetamides react with aldehydes in the presence of catalytic quantities of Cu(acac)₂ (5 mol%) and tetrahydrothiophene (20 mol%) to give glycidic amides in good yields and high diastereoselectivity.