Journal of the Chemical Society. Perkin transactions I p. 2745 - 2748 (1990)
Update date:2022-09-26
Topics:
Kirk, David N.
Smith, Carmen Z.
Varley, Michael J.
Honour, John W.
<19-2H3>Progesterone has been prepared from 3,3:20,20-bisethylenedioxy<19-2H3>pregn-5-en-19-ol by reduction of the derived 19-toluene-p-sulphonate with lithium triethylborodeuteride ('superdeuteride') followed by hydrolysis of the ethylenedioxy groups. <18-2H3>Progesterone was obtained from (20R)-3β-acetoxy-pregn-5-eno-20,18-lactone via conversion into methyl (20R)-3β-20-dihydroxypregn-5-en-18-oate: a two-stage introduction of three atoms of deuterium at C-18 via the toluene-p-sulphonate of the derived <18-2H2>-18-ol required unusual experimental conditions.
View MoreJiangsu Haian Petro chemical Plant
Contact:+86-513-88902723
Address:99, Changjiang West Road, Haian County, Jiangsu
Shenzhen Sungening Medicine Co., Ltd
Contact:+86-871-65110906
Address:Room702, Building 2, 365 Dianchi Road, Kunming, Yunnan Province, P.R. China
Guangxi Nanning Guangtai Agriculture Chemical Co.,Ltd
Contact:+86-771-2311266
Address:Room703,Building12, Software Park Phase II,NO.68,Keyuan Road,Nanning City,Guangxi,China
Henan zhongda Biological Engineering Co., Ltd
Contact:86-28-18109029985
Address:shenzhou road,xuedian industrial estate,zhengzhou city,henan province CHN
Xiamen Huasing Chemicals Co.Ltd.
Contact:0086-592-6228397
Address:NO.24, Xinglin North 2nd Road,Jimei district
Doi:10.1016/S0040-4039(00)97202-2
(1990)Doi:10.1016/S0040-4020(01)90090-0
(1990)Doi:10.1055/s-0030-1260466
(2011)Doi:10.3390/molecules25071610
(2020)Doi:10.1002/anie.201102398
(2011)Doi:10.1021/ol201898x
(2011)
