Quaternary Salts of 2-imidazole. 4. Effect of Various Side-Chain Substituents on Therapeutic Activity against Anticholinesterase Intoxication

DOI: 10.1021/jm00108a019

Source and publish data:

Journal of Medicinal Chemistry p. 1363 - 1368 (1991)

Update date:2022-08-04

Topics:

Authors:

Goff, Dane A.

Koolpe, Gary A.

Kelson, Andrew B.

Vu, Huynh M.

Taylor, Dorris L.

et al. et al.

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Article abstract of DOI:10.1021/jm00108a019

A series of quaternary salt derivatives of 2-<(hydroxyimino)methyl>-1-methylimidazole incorporating various side chains bearing ether, silyl, nitrile, ester, halogen, nitro, sulfone, amino, or aminosulfonyl substituents was prepared and evaluated in vivo

Full text of DOI:10.1021/jm00108a019

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