Radiosynthesis and micro-SPECT analysis of triazole-based RGD integrin ligands as non-peptide molecular imaging probes for angiogenesis

Article abstract of DOI:10.1016/j.bmc.2014.12.065

Taking advantage of click chemistry, we synthesized triazole-containing RGD peptidomimetics capable of binding to α_vβ₃ integrin with diverse potency, and selected ¹²⁵I-labeled compounds proved to interact in vitro and in v