
Journal of Medicinal Chemistry p. 2610 - 2617 (1992)
Update date:2022-07-29
Topics:
Das, Jagabandhu
Floyd, David M.
Kimball, S. David
Duff, Keith J.
Lago, Michael W.
et al.
We have shown that the pyrrolidinylmethyl substituent on the lactam nitrogen (N1) of benzazepinone and benzothiazepinone calcim channel blocking agents is resistant to metabolic deamination and generally increase the duration and potency of antihypertensi
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