Tetrahedron Letters p. 383 - 386 (1991)
Update date:2022-07-29
Topics:
Tanabe, Yoo
Kubota, Yoshi-no
Sanemitsu, Yuzuru
Itaya, Nobushige
Suzukamo, Gohfu
Two distinctive methods for the synthesis of cis- and trans-2,5-disubstituted thiazolidin-4-ones via stereoselective cyclo-condensation between α-mercaptocarboxylic esters and arylimines have been developed.With the new reaction used as the key step, two sets of optically active anti-PAF active thiazolidin-4-ones were synthesized.
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