Functional Group Substitutions as Probes of Hydrogen Bonding between GA Mismatches in RNA Internal Loops

DOI: 10.1021/ja00011a039

Source and publish data:

Journal of the American Chemical Society p. 4313 - 4322 (1991)

Update date:2022-08-05

Topics:

Authors:

Santalucia Jr., John

Kierzek, Ryszard

Turner, Douglas H.

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Article abstract of DOI:10.1021/ja00011a039

The contribution of hydrogen bonding to the stability of GA mismatches in RNA is investigated by making functional group substitutions. Such substitutions are made possible by the chemical synthesis of RNA; chemical incorporation of purine riboside and 2-

Full text of DOI:10.1021/ja00011a039

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