Nucleoside Phosphite, 0-Bis(1,1,1,3,3,3-hexafluoro-2-propyl) Deoxyribonucleosid-3'-yl Phospites. A Versatile Synthetic Intermediate for Phosphonate Modified Nucleotide and Oligonucleotide Synthesis

Article abstract of DOI:10.1246/cl.1992.935

The 0-bis(1,1,1,3,3,3-hexa-fluoro-2-propyl) deoxyribonucleosid-3'-yl phosphite units could be converted into the 0-nucleosid-3'-yl phosphonate, 0-2-cyanoethyl 0-nucleosid-3'-yl phosphonate, and 0-1,1,1,3,3,3-hexafluoro-2-propyl 0-nucleosid-3'yl phosphonot