Nucleoside Phosphite, 0-Bis(1,1,1,3,3,3-hexafluoro-2-propyl) Deoxyribonucleosid-3'-yl Phospites. A Versatile Synthetic Intermediate for Phosphonate Modified Nucleotide and Oligonucleotide Synthesis

DOI: 10.1246/cl.1992.935

Source and publish data:

Chemistry Letters p. 935 - 938 (1992)

Update date:2022-08-04

Topics:

Authors:

Hosaka, Hideo

Nakamura, Hiroyuki

Funakoshi, Hidenori

Takaku, Hiroshi

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Article abstract of DOI:10.1246/cl.1992.935

The 0-bis(1,1,1,3,3,3-hexa-fluoro-2-propyl) deoxyribonucleosid-3'-yl phosphite units could be converted into the 0-nucleosid-3'-yl phosphonate, 0-2-cyanoethyl 0-nucleosid-3'-yl phosphonate, and 0-1,1,1,3,3,3-hexafluoro-2-propyl 0-nucleosid-3'yl phosphonot

Full text of DOI:10.1246/cl.1992.935

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