Chemical and Pharmaceutical Bulletin p. 121 - 129 (1995)
Update date:2022-08-02
Topics:
Ikeya
Sugama
Tanaka
Wakamatsu
Ono
Takeda
Oyama
Maruno
After oral administration of schizandrin (1) to rat, the bile was collected and treated with β-glucuronidase and arylsulfatase. Eleven metabolites, SZ-M0 (3), SZ-M1 (4), SZ-M2 (5), SZ-M3 (6), SZ-M4 (7), SZ-MS (8), SZ M6 (9), SZ-M7 (10), SZ-M8 (11), SZ-M9 (12) and SZ-M10 (13) were isolated from the bile treated with the enzymes. The bile after oral administration of 1 to dog was collected and treated with enzymes in the same way, and eight metabolites, 3-8, 10 and SZ-MD2 (14) were isolated from the bile treated with enzymes. The structures of these metabolites were determined on the basis of chemical and spectral studies. The major metabolite in the bile of rat was 7 and the major metabolites in the bile of dog were 7 and 14.
View MoreXinjiang Fufeng Biotechnologies Co., Ltd.
Contact:+86-539-7287111
Address:GANQUANPU INDUSTRIAL PARK, ECONOMIC AND TECHNOLOGICAL DEVELOPMENT AREA (TOUTUNHE DISTRICT) OF URUMQI
Zhangjiagang Golden Reach Fine Chemical Co.,LTD.
Contact:+86-512-6585 6968
Address:Changfu Road, Dongsha Chemical Industry Park, Zhangjiagang City, Jiangsu Province, China
Contact:86-21-57725962
Address:shanghai
Contact:852-29282288
Address:HONGKONG
Shanghai Sunwise Chemical Co., Ltd
website:http://www.sunwisechem.com
Contact:86-021-33883180
Address:Room 10E, Building G, Westlink Center, No. 2337 Gudai Road, Minhang District, Shanghai, China PC: 201100
Doi:10.1002/adsc.201600485
(2016)Doi:10.1016/0040-4039(90)80222-8
(1990)Doi:10.1016/j.bmcl.2011.03.112
(2011)Doi:10.1016/S0022-1139(00)82604-4
(1990)Doi:10.1021/acs.orglett.9b04202
(2019)Doi:10.1016/S0040-4020(01)85453-3
(1990)