An efficient synthesis of optically active 2-alkylsuccinate monoesters

Article abstract of DOI:10.1055/s-1991-26405

Optically active 2-alkylsuccinates were obtained as their monoesters by stereospecific substitution of the p-toluenesulfonates or p-nitrobenzenesulfonates of α-hydroxy esters with sodium di-tert-butyl malonate, followed by hydrolysis and decarboxylation of the resulting diacids.