Synthesis and evaluation of 1-(4-[18F]fluoroethyl)-7-(4′- methyl)curcumin with improved brain permeability for β-amyloid plaque imaging

DOI: 10.1016/j.bmcl.2011.08.003

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 5765 - 5769 (2011)

Update date:2022-09-26

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Authors:

Lee, Iljung

Yang, Jehoon

Lee, Jung Hee

Choe, Yearn Seong

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Article abstract of DOI:10.1016/j.bmcl.2011.08.003

Alzheimer's disease is characterized by the accumulation of β-amyloid (Aβ) plaques and neurofibrillary tangles (NFTs) in the brain. We previously developed [¹⁸F]fluoropropylcurcumin ([¹⁸F]FP-curcumin), which demonstrated excellent bi

Full text of DOI:10.1016/j.bmcl.2011.08.003

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