Synthesis and cytotoxic activity of 2,5-disubstituted pyrimido[5,4-c] quinoline derivatives

DOI: 10.1016/j.cclet.2011.05.030

Source and publish data:

Chinese Chemical Letters p. 1277 - 1280 (2011)

Update date:2022-08-03

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Authors:

Zhang, Fan

Zhai, Xin

Chen, Li Juan

Qi, Jian Guo

Cui, Bo Cui, Bo

Gu, Yu Cheng

Gong, Ping

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Article abstract of DOI:10.1016/j.cclet.2011.05.030

A series of 2,5-disubstituted pyrimido[5,4-c]quinoline derivatives were synthesized and their cytotoxic activity against H460, HT-29 and MDA-MB-231 cell lines was evaluated in vitro. It was found that most of the tested compounds especially compound 17, s

Full text of DOI:10.1016/j.cclet.2011.05.030

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