Carbanion addition to acetylenes: An efficient stereoselective route to α-methylene-γ-lactams

DOI: 10.1016/S0040-4039(00)79668-7

Source and publish data:

Tetrahedron Letters p. 1363 - 1366 (1991)

Update date:2022-08-03

Topics:

Authors:

Patra Patra

Maiti Maiti

Chatterjee

Chakravarty

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Article abstract of DOI:10.1016/S0040-4039(00)79668-7

Intramolecular addition of carbanions, derived from the acetylenic amides (5b,d), (7) and (9) has been shown to be highly stereoselective leading to the α-methylene-γ-lactam derivatives (6a,b), (8a,b) and (10).

Full text of DOI:10.1016/S0040-4039(00)79668-7

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