Pseudopeptide analogues of substance P and leucine enkephalinamide containing the Ψ(CH2O) modification: Synthesis and biological activity

DOI: 10.1021/jm00112a018

Source and publish data:

Journal of Medicinal Chemistry p. 2430 - 2438 (1991)

Update date:2022-07-29

Topics:

Authors:

Roubini Roubini

Laufer Laufer

Gilon Gilon

Selinger

Roques Roques

Chorev Chorev

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00112a018

The isosteric methyleneoxy Ψ(CH₂O) function was employed as a novel peptide-bond surrogate and incorporated into sequences of two neuropeptides, substance P (SP) and enkephalin. A pseudopeptide analogue [pGlu⁶,Phe⁸Ψ(CH View More

Full text of DOI:10.1021/jm00112a018

Products guided by the article

Product name:Boc-Phe-PheΨ(CH2O)Gly-Leu-Met-NH2

Cas No:133851-85-1

R&D Labs maybe for 133851-85-1

Taixing Joxin Bio-tec Co.,Ltd.

website:http://www.joxbio.com

Contact:86-523-87558858 87612088

Address:No.88, chengdong industrial park
Changsha Kamer Essence and Flavor Co.,Ltd

Contact:86-731-89832270

Address:No.327 Kangnin Road Changsha Bio Information Industry Park, Changsha city, Hunan province
Suzhou Time-chem Technologies Co., Ltd.

Contact:0512-63983931/68086856

Address:No. 1326 of Binhe Road, New District, Suzhou, Jiangsu, P. R. China
Anhui Charm Imp.&Exp.Co., Ltd

website:http://www.chinacharm.cn/

Contact:86 551 5316260

Address:No. 211,XiangZhang Road,Hefei City,Anhui Province,China
Shanghai WinTide BioTechnology Co.,Ltd

Contact:86-21-37100630

Address:No. 908 Yunhe Road, Fengxian district, Shanghai

Relevant to this article

Metal-free enantioselective hydroxyamination of aldehydes with nitrosocarbonyl compounds catalyzed by an axially chiral amine

Doi:10.1021/ja4099627
(2013)
Synthesis of novel 6′-spirocyclopropyl-5′-norcarbocyclic adenosine phosphonic acid analogues as potent anti-HIV agents

Doi:10.1080/15257770.2011.602656
(2011)
Synthesis of N-α-BOC-N-ε-tribenzyl EDTA-L-lysine. An amino acid analogue suitable for solid phase peptide synthesis

Doi:10.1016/S0040-4020(01)81787-7
(1991)
Behavior of 2-iminothiazolidin-4-one with different reagents

Doi:10.1002/jhet.628
(2011)
P-Stereogenic β-Aminophosphines: Preparation and Applications in Enantioselective Organocatalysis

Doi:10.1021/acs.joc.7b00199
(2017)
Syntheses of 2′-deoxy-2′-fluoro-β-d-arabinofuranosyl purine nucleosides via selective glycosylation reactions of potassium salts of purine derivatives with the glycosyl bromide

Doi:10.1016/j.tetlet.2015.11.091
(2016)

Article Doi