A new approach to the synthesis of enantiomerically pure 2,3-diaminoacids through chiral imidazolidin-2-ones

Article abstract of DOI:10.1016/S0040-4020(01)96136-8

The synthesis of enantiomerically pure 5-iodomethylimidazolidin-2-ones (3a-c) and (4a-c) is reported, by means of iodocyclisation of allylic tosylureas (2a-c). Starting from pure (3a) and (4a), a synthesis of both (R)- and (S)-2,3-diaminopropanoic acid is