Efficient synthesis of β-CF3/SCF3-substituted carbonyls via copper-catalyzed electrophilic ring-opening cross-coupling of cyclopropanols

DOI: 10.1021/acs.orglett.5b00782

Source and publish data:

Organic Letters p. 2186 - 2189 (2015)

Update date:2022-07-29

Topics:

Authors:

Li, Yong

Ye, Zhishi

Bellman, Tabitha M.

Chi, Teng

Dai, Mingji

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Article abstract of DOI:10.1021/acs.orglett.5b00782

The first copper-catalyzed ring-opening electrophilic trifluoromethylation and trifluoromethylthiolation of cyclopropanols to form C_sp3-CF₃ and C_sp3-SCF₃ bonds have been realized. These transformations are effic

Full text of DOI:10.1021/acs.orglett.5b00782

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