A novel synthesis of esters via substitution of the benzotriazolyl group in 1-(benzotriazol-1-yl)alkyl esters with organozinc reagents

Article abstract of DOI:10.1055/s-1991-26382

Aldehydes are converted by thionyl chloride and benzotriazole into 1-(1-chloroalyl)benzotriazoles which react with sodium carboxylates to give 1-(benzotriazol-1-yl)alkyl esters. 3. In the alternative route, 3 are prepared by substitution of one of the acetoxy groups in acylals with benzotriazole. The benzotriazolyl moiety in 3 is substituted by an alkyl, an aryl or an alkynyl group upon treatment with an organic reagent in a new versatile synthesis of esters 4.