Journal of Medicinal Chemistry p. 425 - 432 (1993)
Update date:2022-09-26
Topics:
Burke Jr.
Lim
Marquez
Li
Bolen
Stefanova
Horak
A study was undertaken to prepare inhibitors of the lymphocyte protein- tyrosine kinase p56(lck). Using the known p56(lck) inhibitor 3,4-dihydroxy- α-cyanocinnamamide (4) as a lead compound, bicyclic analogues were designed as conformationally constrained
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(1960)
