Journal of Medicinal Chemistry p. 389 - 397 (1992)
Update date:2022-09-26
Topics:
Meanwell, Nicholas A.
Rosenfeld, Michael J.
Wright, J. J. Kim
Brassard, Catherine L.
Buchanan, John O.
et al.
A series of phenylated pyrazoloalkanoic acid derivatives were synthesized and evaluated as inhibitors of ADP-induced human platelet aggregation. 3,4,5-Triphenyl-1H-pyrazole-1-nonanoic acid (8d), with an IC50 of 0.4 μM, was the most potent inhibitor identi
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