
Carbohydrate Research p. 21 - 28 (1988)
Update date:2022-08-03
Topics:
Herzig, Jacob
Nudelman, Abraham
Gottlieb, Hugo E.
A simple, regioselective O-deacetylation procedure is described which involves =0.5 equiv. of Bu3SnOMe or Bu2SnO in methanol.Anomeric acetates are considerably more reactive than primary and secondary acetates, thereby enabling selective removal, to give ca.70percent of products with HO-1 unsubstituted.Prolonged reaction resulted in complete deacetylation.Secondary acetates were removed faster than primary acetates and the overall rates of reaction were influenced greatly by the anomeric substituent in the order of OAc >> OH > OMe.No acyl migration took place under the reaction conditions.
View MoreMTT Pharma & Bio-technology Co.,Ltd(expird)
Contact:+86-21-58407925
Address:Room2019, Building C, Tomson Center, No.158, Zhang Yang Road, Shanghai, China
zhengzhou Triz Pharma-Tech Co., Ltd
website:http://www.Trizpharma-tech.com
Contact:+86-0371-86597269,53392065
Address:High-tech Industrial Development Zone, Zhengzhou City, NO.7 Holly Street
Contact:+86 755 26588093
Address:No.9 Linkong West Street, Hengdian Street, Huangpi District, Wuhan City, China.
HaiNan Periwinkle Pharmaceutical Co.,Ltd.
website:http://www.cchpharm.com/en/index.html
Contact:020-82208978
Address:Gongye road,Wuzhishan city,HaiNan province
Zhejiang Linhai Xinhua Chemicals Factory
Contact:0086-13661858911
Address:Xunqiao Development Zone, Linhai, Zhejiang, China
Doi:10.1016/j.tetlet.2011.09.035
(2011)Doi:10.1016/j.bmc.2012.05.051
(2012)Doi:10.1039/c8ob00841h
(2018)Doi:10.1021/jo201988m
(2012)Doi:10.1134/S1070428020060147
(2020)Doi:10.1021/jm00112a039
(1991)