Carbohydrate Research p. 21 - 28 (1988)
Update date:2022-08-03
Topics:
Herzig, Jacob
Nudelman, Abraham
Gottlieb, Hugo E.
A simple, regioselective O-deacetylation procedure is described which involves =0.5 equiv. of Bu3SnOMe or Bu2SnO in methanol.Anomeric acetates are considerably more reactive than primary and secondary acetates, thereby enabling selective removal, to give ca.70percent of products with HO-1 unsubstituted.Prolonged reaction resulted in complete deacetylation.Secondary acetates were removed faster than primary acetates and the overall rates of reaction were influenced greatly by the anomeric substituent in the order of OAc >> OH > OMe.No acyl migration took place under the reaction conditions.
View MoreGuangzhou Flower's Song Fine Chemical CO,. Ltd
Contact:+86-20-87475199
Address:No.12, Fenghuang 3 Road, Jiulong Industrial Park, Luogang District, Guangzhou. China
Xinxiang Junlong Biological Technology Co., Ltd.
website:https://junlongbio.lookchem.com/
Contact:86-13525059581
Address:Xinxiang City, Henan Province
Jiangxi Hessence Chemicals Co., Ltd.
Contact:+86 796 3511924
Address:Chengxi Industrial Park, Jishui County, Jiangxi Province 331600 China.
Jintan Jinnuo Chemical Co., Ltd.
Contact:+86-519-80199901
Address:Room 1804, Building 1, Huacheng Business Plaza, Jintan, Jiangsu, China
Guangzhou Probig Fine Chemical Co., Ltd.
Contact:020-86297874
Address:No.2, 1/F, No.20, Hetai Road,Hebian Village, Baiyun District,Guangzhou,China
Doi:10.1016/j.tetlet.2011.09.035
(2011)Doi:10.1016/j.bmc.2012.05.051
(2012)Doi:10.1039/c8ob00841h
(2018)Doi:10.1021/jo201988m
(2012)Doi:10.1134/S1070428020060147
(2020)Doi:10.1021/jm00112a039
(1991)