A concise synthesis of tetrabenazine: An intramolecular aza-prins-type cyclization via oxidative c-h activation

Article abstract of DOI:10.1021/ol202792q

A concise synthesis of tetrabenazine and dihydrotetrabenazine is described. The key feature of this synthesis is the intramolecular aza-Prins-type cyclization of an amino allylsilane via oxidative C-H activation. 2011 American Chemical Society.