
Chemistry Letters p. 1795 - 1798 (1982)
Update date:2022-08-02
Topics:
Fujisawa, Tamotsu
Takeuchi, Masashi
Sato, Toshio
The use of 3-alkenoate as a masked synthon of 4-oxo-2-alkenoate was established by a three step conversion of 3-noneonate into 4-oxo-2-nonenoate through epoxidation, isomerization to an allyl silyl ether, and oxidation in a high overall yield.This method was applied to the short step synthesis of pyrenophorin from 7-oxo-3-octenoic acid.
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