Radical cyclization cascades of unsaturated Meldrum's acid derivatives

DOI: 10.1021/ol2029367

Source and publish data:

Organic Letters p. 146 - 149 (2012)

Update date:2022-08-03

Topics:

Authors:

Sautier, Brice

Lyons, Sarah E.

Webb, Michael R.

Procter, David J.

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Article abstract of DOI:10.1021/ol2029367

Unsaturated, differentially substituted Meldrum's acid derivatives undergo cascade cyclizations upon ester reduction with SmI₂-H₂O. The cascade cyclizations proceed in good yield and with high diastereocontrol and convert simple, ach

Full text of DOI:10.1021/ol2029367

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